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However, while these drugs provide significant benefits, they have also been linked to an increased risk of gallbladder problems, including gallstones (cholelithiasis) and inflammation of the gallbladder (cholecystitis), especially when used for a long time or at high doses

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It can stimulate the release of insulin, growth hormone (which aids in muscle growth and fat reduction), and other substances

So, when someone goes on weight-loss drugs and substantially reduces their food intake, the likelihood of deficiencies becomes even greater, unless they change their diet to include more nutrient-dense foods. Why protein matters on GLP-1s Gilbert recommends focusing on nutrient density and protein intake above all else