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Histopathological alterations caused by fluoride includes thyroid follicular cell apoptosis, necrosis, and hyperplasia of thyroid gland

Randomized controlled trials have shown that leucovorin can improve speech and behavior, although more extensive studies are needed

Glutathione supplements may help with detoxification, support immune function, and protect against oxidative stress, contributing to overall health and wellness

The first heart sound (S1) represents closure of the atrioventricular (mitral and tricuspid) valves as the ventricular pressures exceed atrial pressures at the beginning of systole (point a)

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Lu and Holmgren, 2009