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[DOI] [PubMed] [Google Scholar] 52.Li J., Mao M., Li J., Chen Z., Ji Y., Kong J., Wang Z., Zhang J., Wang Y., Liang W., et al

10.1016/j.cell.2004.11.035 43 GrayE

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Specifically, intake of an FMD has been shown to reactivate T eff cells that underwent early exhaustion, shift cancer metabolism from glycolytic to OXPHOS, and reduce the collagen deposition rate

This study innovatively focuses on the mechanism by which FOXO4-DRI induces apoptosis in senescent endothelial cells, demonstrating that it functions by activating the p53/BCL-2/Caspase-3 signaling pathway to promote selective apoptosis of these cells