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In addition to the VHL-HIF-VEGF/vascular endothelial growth factor receptor (VEGFR) pathway, VHL mutations affect signaling regulation in the mTOR and epidermal growth factor receptor (EGFR) pathways, promoting tumor growth (130)

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Regarding her social history, she denied use of alcohol, had no smoking history, or use of recreational drugs

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Which one fits you is a clinical decision made with your provider

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