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However, it has very low bioavailability

Figure 3 In the context of T1D, the populations of resident islet macrophages in both animal models and humans display an pro-inflammatory phenotype, characterized by the secretion of cytokines (such as IL-1 and TNF), upregulated expression of MHC-II and increased antigen presentation capacity, and decreased phagocytosis of apoptotic -cells (57)