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Prescribing patterns may provide early insight into how physicians and patients anticipate changing cost dynamics, even before those changes are fully realized at the pharmacy counter

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14 Of the remaining acetaminophen, approximately 2% is excreted unchanged in the urine and the rest undergoes CYP450-mediated oxidation to form a reactive metabolite, N -acetyl- p -benzoquinone imine (NAPQI)

PeerJ 9:119