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Neuropathological investigations in the substantia nigra pars compacta of Parkinsons disease patients demonstrate that deficient PGC-1 expression compromises mitochondrial biogenesis and disrupts the coordinated transcriptional activation of antioxidant stress-responsive gene networks, thereby precipitating dopaminergic neuronal degeneration (Piccinin et al., 2021)

Glucagon-like peptide 1 improves insulin resistance in vitro through anti-inflammation of macrophages

Significantly increased phosphorylated Akt (Ser-473 and Thr-308) protein expression in the pancreas compared to the high-selenium alone group

World J Stem Cells

Vos, Evert

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