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GLP-1 success story: Jill Sweeney, 54, lost 130 lbs After lifelong weight issues, Jill Sweeney was diagnosed with raging diabetes and put on Mounjaro

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In a model of non-ischemic HF in dogs (tachycardiomyopathy induced by pacemakers), IV infusion of GLP-1 increases left ventricular (LV) contractility (LV dP/dt increased by 98%, stroke volume by 102%, and cardiac output by 57%) and decreases LV end-diastolic pressure, heart rate, and systemic vascular resistance