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GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled

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Key Clinical Benefits of Semaglutide GLP-1 Therapy Clinical trials including the SUSTAIN and STEP programmes have confirmed semaglutides broad therapeutic profile: Superior Blood Sugar Control Semaglutide consistently reduces HbA1c by up to 1.8% from baseline one of the most significant reductions among GLP-1 receptor agonists available