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Mechanistically, elevated SLC25A39 levels correlated with reduced reactive oxygen species (ROS) accumulation in CRC

When levels drop, the immune system loses some of its responsiveness

Conceptually, ageing reduces the functional capacity of all organs and systems, ultimately weakening the whole organism, reducing its adaptability, wearing out its defensive systems and bringing it to death through age-dependent diseases

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doi: 10.1111/j.0954-6820.1988.tb15891.x

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