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KPV has been studied in cell and animal models related to intestinal inflammation, but it should not be viewed as a proven treatment for Crohns disease, ulcerative colitis, or other inflammatory bowel diseases

The absence of the Y2 receptor in human and murine pancreatic islets corresponds to the lack of a direct effect of PYY 336 on glucose-stimulated insulin secretion (78)

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Although limited by a small sample size, the research is valuable as a pilot study that demonstrates a relationship, said CDM resident and coauthor Kevin Lee, DDS, MD

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Some of these studies found an association but none of them found a causal link