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I outlined this in the Peptides deep dive in the Missing Context Newsletter
It remains unclear whether diet-induced differences in microbial composition, or other mechanisms such as transcriptional or post-transcriptional regulation of microbial enzymes (or more likely a combination), are responsible for the functional differences observed
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FDA-approved compounds have robust safety data
not trial-validated Endpoint Skin density (instrument-measured) Topical timeline 12 weeks Injectable framing Anecdotal
A subset of samples was also prepared in degassed water under oxygen-free conditions in an anaerobic glovebox (Coylab) or under aerobic conditions following bubbling under N 2 gas for 1 h with continuous stirring in a round bottom flask
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