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This study demonstrated that semaglutide significantly reduced the risk of major adverse cardiovascular events (MACE) by 26% compared with placebo in patients with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors

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Penn D, Dolderer M, Schmidt-Sommerfeld E

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For example, vitamin B3 (niacin) supports NAD+, a coenzyme essential for mitochondrial energy reactions