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doi: 10.1016/j.cgh.2015.02.019 230 SugimotoKIkeyaKBambaSAndohAYamasakiHMitsuyamaKet al

There are some data to suggest that insulin resistance also occurs in PD [70], however, this is controversial since systemic insulin resistance is not present in de novo, medication-free PD patients [71], and brain insulin resistance is not present in cognitively normal PD cases [72]