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Technical Article
Gramer, Gwendolyn et al
With a B12 deficiency, the body may produce fragile red blood cells that break down more easily, releasing a yellow pigment called bilirubin
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Neurological symptoms often develop gradually and may include: Paraesthesia : tingling or 'pins and needles' sensations, typically starting in the feet and hands Numbness : reduced sensation in the extremities, which may affect balance and coordination Burning pain : particularly in the feet, often worse at night Weakness : muscle weakness and difficulty walking Balance problems : unsteady gait and increased fall risk due to proprioceptive impairment Cognitive changes : memory problems, confusion, difficulty concentrating, and mood disturbances Haematological signs may accompany neurological symptoms and include fatigue, weakness, pallor, and shortness of breath due to megaloblastic anaemia
Advertisement | page continues below Some studies suggest that babies born to women with low levels of vitamin B12 during pregnancy may have an increased risk of neural tube defects
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