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Therefore, monitoring thyroid parameters is advised when oral semaglutide is co-administered.45,160 In summary, most of the studied drugs did not show clinically significant DDIs related to delayed gastric emptying caused by GLP-1 RAs or a dual GLP-1/GIP RA administration

Studies show that GLP-1 receptor agonists can reduce BMI by an average of 1.59 kg/m and body weight by 3.57 kg (about 7.9 lbs) compared to metformin or placebo

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[DOI] [PubMed] [Google Scholar] 35.van Zuuren E.J., Albusta A.Y., Fedorowicz Z., Carter B., Pijl H