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[46] [47] There is evidence that the conversion proceeds by removal of the phytyl tail of K 1 to produce menadione (also referred to as vitamin K 3 ) as an intermediate, which is then prenylated to produce MK-4

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Both drug classes address weight loss, but through fundamentally different biological routes

Anti-proliferative effect inhibits cell division, prevents restenosis High lipophilicity ensures rapid uptake & sustained retention in vessel wall