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Additionally, the increased MDA levels observed upon SYNCRIP depletion were significantly reduced following SYNCRIP restoration (Figure 3E-G), further linking SYNCRIP function to suppression of ferroptosis

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Prevention of oxidative damage and maintenance of mitochondrial function The neuroprotective behavior displayed by Sp intrigued a parallel study in the Drosophila eye since it displays detectable phenotypes in response to neurophysiological disruptions such as progressive loss of ommatidia accompanied with disrupted rhabdomere arrangement 38