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The amino acid sequence of semaglutide itself and the fatty acid side chain act as metabolic substrates after intestinal absorption, affecting the bodys metabolism

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For example, the Wegovy prescribing information notes, Coadministration with other semaglutide-containing products or with any other GLP-1 receptor agonist is not recommended. Similarly, the Zepbound prescribing information notes, Coadministration with other tirzepatide-containing products or with any GLP-1 receptor agonist is not recommended. Side effects of taking semaglutide with tirzepatide Semaglutide and tirzepatide have long lists of potential side effects