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Los receptores GLP-1 estn presentes en diversos tejidos del cuerpo, incluyendo el pncreas, el cerebro, el corazn y el tracto gastrointestinal

This can decrease the synthesis of 5-methyltetrahydrofolate and thus the remethylation of homocysteine

However, it is essential to note that the intranasal route avoids pre-absorption metabolism, first-pass effect, and dilution caused by distribution along with protein binding, indicating that the required intranasal volume may easily be as low as 0.011% of oral dosage [182]

American Cancer Society nutrition and physical activity guideline for cancer survivors

Journal reference: Song G, Han H, Park S, et al

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