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GLP-1s shut down the noise on less-than-stellar behaviors that can age you quick

In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid (MPTP/P)-induced Parkinsons disease model mice, MPTP/P injection increased the ratio of Bax/Bcl-2 and the expression of caspase-3 in the hippocampus, while berberine administration reversed these effects ( In addition, animal experiments and cell experiments have confirmed that berberine reduces the levels of extracellular and intracellular A, increases the levels of LC3-II, Beclin-1, hVps34 and cathepsin-D, and reduced the levels of P62, Bcl-2, amyloid precursor protein (APP), and beta-secretase 1 (BACE1)

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Intermittent fasting is a diet that is based around regular cycles of eating and fasting

doi:10.3346/jkms.2015.30.9.1213 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( Source: Wieers, Michiel L A J et al