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Maintenance doses vary based on individual response, clinical goals, and tolerance

While administration of caffeine was also associated with a mean improvement of the total cognition composite by 7.70 compared to placebo, this mean difference was not statistically significant (p = 0.148, Cohens d = 0.697)

Cell 177 , 19331947 (2019)

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doi:10.1042/CS20171299 32

So lots of more and more studies are looking at and coming out with, um, you know, It's correlation with improved cognitive function as we age in the realm of Alzheimer's, dementia, it's neuroprotective [00:38:00] benefits from an inflammatory perspective, from a blood sugar, insulin perspective and again, You know, Alzheimer's dementia is a big, big medical burden in our country and is heavily tied in to blood sugar