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Regardless of suspected causal relationship with the study drug, all observed AE were reported (Table 5) including 13.3% of patients exposed to ALC ( n =4) and 7.7% of those receiving placebo ( n =2) who experienced at least one AE during the course of the trial

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Signs and Symptoms of Vitamin B12 Deficiency Vitamin B12 deficiency is characterized by megaloblastic anemia, fatigue, weakness, constipation, loss of appetite, and weight loss