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Mens GIP og GLP-1 primrt modulerer insulinsekretion og centralnervst styrer mthedsfornemmelsen, bner den yderligere aktivering af glucagonreceptoren en helt ny metabolisk signalvej
V.GueriguianJ
J Clin Endocrinol Metab 93(6):21812187 Johnson KC, Bray GA, Cheskin LJ, Clark JM, Egan CM, Foreyt JP et al (2017) The effect of intentional weight loss on fracture risk in persons with diabetes: results from the Look AHEAD randomized clinical trial
For the Bridge, its weight management paired with a qualifying BMI: 35 or higher on its own, or a lower BMI (30+ or 27+) combined with a specific condition like a heart, kidney, or blood pressure issue, pre-diabetes, or a history of heart attack or stroke
Franceschi C, Capri M, Monti D, Giunta S, Olivieri F, et al
Clinical studies of GLP-1 receptor agonists have shown increased rates of gallbladder events compared to placebo
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