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Common initial side effects may include: Importantly, side effects tend to improve over time with continued use

GLP-1 RAs reduce food intake and inhibit gastric emptying by activating GLP-1R+ cells in the nervous system, resulting in weight loss ( de novo lipogenesis (DNL) in the liver ( in vivo ( In contrast, GLP-1R is present on human hepatocytes, which may regulate hepatic pathological processes directly in MASLD

Pregnancy and breastfeeding : Inform your doctor if you are pregnant, breastfeeding, or planning to become pregnant soon

In contrast, older drugs like phentermine typically result in more modest weight loss and more side effects

If youre ready to explore medically assisted weight management right now, Noom Med can pair you with a clinician to evaluate your options and build a plan that fits your goals