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It usually results from genetic factors, excessive calorie intake, and metabolic issues

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Matsumura T, Sato T, Abe T, Sanjo H, Katagiri K, Kimura H, et al

Gut microbiota and gut-derived metabolites are altered and associated with dietary intake in women with polycystic ovary syndrome

Bariatric surgery has been found to improve glucose and lipid metabolism independently of weight loss, and multiple studies indicate bariatric surgery may lead to resolution of NAFLD and NASH and reverse early-stage fibrosis