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Despite relatively high prevalence of both conditions and their debilitating impact on life (for example, one-quarter of ME/CFS patients are bed- or house-bound) [6], the understanding of mechanisms leading to the development of fatigue is poor

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doi:10.1016/S1262-3636(17)30067-8 23

To find out, Patell's team tracked outcomes for more than 558,000 Americans enrolled in a major health care database