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Interestingly, the number of mitochondria in synapses is very high

Thus, niclosamide, at relatively low concentrations, in only the tens of micromolar range, basically turns down the dimmer switch on the cells energy production while still preserving reversible viability (33)

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But with todays hygiene standards of food products, most people arent able to ingest trace amounts of soil with their fruits and vegetables, so they dont get B12

In addition to GSH inhibition, LCS3 is reported to inhibit the activity of thioredoxin reductase1 (TXNRD1), a critical antioxidant regulator maintaining the redox state of thioredoxin (TRX) [19](Supplementary Fig