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Atrophic astrocytes in aged marmosets present tau hyperphosphorylation, RNA oxidation, and DNA fragmentation

Breckenridge, CO, US

PMCID: PMC2699646 Sinha, D

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761 The overexpression of CYP1B1 increases the ubiquitination and degradation of ACSL4, and melatonin could inhibit ferroptosis by regulating the ACSL4/CYP1B1 pathway, significantly reducing the cerebral ischemic area and neuron loss in MCAO mice