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Peak GH levels occur during puberty, and by middle age, pulsatile GH release has declined substantially

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published an audit of women inadvertently exposed to GLP-1 receptor agonists in the first trimester of pregnancy and reported no increase in the risk of major congenital malformations (adj RR 0.95 (0.721.66), and no increase in the risk of major cardiac malformations (adj RR 0.68 (0.421.12)) [54]