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Synthesis 1-(4-(2,2-Dicyanovinyl)phenyl)-1,2,2-triphenylethene (TPE-DCV) TPE-CHO was prepared according to the previous publication 59

Resources We Trust Mayo Clinic: 5 Nutrition Tips for Chronic Kidney Disease Cleveland Clinic: Improving Management of Diabetes and Chronic Kidney Disease National Kidney Foundation: Diabetes A Major Risk Factor for Kidney Disease American Diabetes Association: Keep Your Kidneys Healthy American Heart Association: The Connection Between Diabetes, Kidney Disease and High Blood Pressure Diabetic Nephropathy (Kidney Disease)

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10.1038/emm.2016.4

Below is the recommended 5-month titration plan: The chart provides a clear visual representation of the dosage schedule and corresponding months, making it easier for you to follow and understand

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