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The major enzyme superfamilies comprise cytochrome P450 monooxygenases (P450s), glutathione S-transferases (GSTs), carboxylesterases (COEs), ATP-binding cassette (ABC) transporters, and UDP-glycosyltransferases (UGTs) [5, 26, 36-39] (Figure 2)

Saxenda is not indicated as a lipid-lowering agent in the manner of statins or fibrates

Knowing the "why" makes the "what to do" much clearer

Move regularly to support metabolism While GLP-1 medications can drive weight loss on their own, combining them with movement and lifestyle support leads to more sustainable results and better health markers

Table 1 provides detailed suggestions on key future directions for clinical study in this area

Mature skin, in particular, can benefit from peptides for their ability to improve skin firmness