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Generally, you shouldnt experience fatigue, low energy, hypoglycemia, or long-term nausea while taking GLP-1s, Obici says

Case reports with a small number of patients are not generalizable, though they do suggest that some women may experience a normal pregnancy if they transition off a GLP-1 medication during the first trimester

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Compounded versions often use unapproved ingredients, such as salt forms of semaglutide, or exceed the recommended dosage guidelines, which increases the risks

GLP-1 therapies reduced inflammatory markers and protected kidney function in animals and humans, including in the FLOW trial

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