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Specifically, NADPH oxidase (NOX) in microglia generates excessive reactive oxygen species (ROS) by transferring electrons across the membrane, leading to excessive cellular depolarization and acidification, which in turn inhibits electron efflux to the extracellular compartment [11,12,13]

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Altered iron levels have been linked to respiratory diseases [50]

Human mesenchymal stromal cells broadly modulate high glucose-induced inflammatory responses of renal proximal tubular cell monolayers

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