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Studies have demonstrated that chronic administration of AOD-9604 leads to adaptive changes in adipose tissue, including increased expression of beta-3 adrenergic receptors and enhanced sensitivity to lipolytic signals

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Research progress Support The animal experiments have achieved remarkable results: In the obese mouse model, after daily subcutaneous injection of AOD 9604 (250 g/kg) for 8 weeks, the body weight of the mice decreased by 12%, the subcutaneous fat mass decreased by 25%, and the weight of epididymal adipose tissue significantly decreased, confirming its effectiveness in fat reduction

doi:10.1038/s41598-024-65310-y Neelakantan H, Hommel JD, Watowich SJ, et al

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