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During the titration period, doses of metformin and glimepiride were to be increased up to 2,000 mg/day and 4 mg/day, respectively

Severe or acute kidney failure: The compound should not be used in patients with significant renal impairment

If you experience any suspected side effects from tirzepatide, report them to the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

The study also could not draw conclusions about younger populations, the researchers acknowledged

Many patients also report a longer-lasting feeling of fullness as a result