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2018;8:a030346

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Such fine modulation of movement across the epithelium demands structural components that aid this process, such as transmembrane proteins including occludin, junctional adhesion molecules, and claudin protein family members that together maintain epithelial cell basolateral polarity (Shin et al

That's also where diabetic peripheral neuropathy adds another layer of complexity impaired circulation and nerve signaling make the already-limited healing environment in foot tissue even harder to overcome without targeted support

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