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doi: 10.3390/nu11051136

The raised flap is entirely dependent on blood flow through small vessels at its base, and any factor that compromises oxygen delivery (anaemia being a major one) puts the flap at risk

These mechanisms support the consistent findings with joint, gut, and soft tissue models

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This lipolytic effect appears to be mediated through activation of 3-adrenergic receptors on adipocytes, which are G-protein coupled receptors that, when activated, stimulate adenylyl cyclase to increase intracellular cAMP levels

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