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10.1038/s41598-018-26296-6 [DOI] [PMC free article] [PubMed] [Google Scholar] Ribas V., Garca-Ruiz C., Fernndez-Checa J

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Healthcare professionals should provide comprehensive lifestyle guidance alongside prescribing these medications

38,39 A MAI Calculator is available at no cost for use here: HOW TO SAFELY DEPRESCRIBE Deprescribing Tools Once polypharmacy and PIMs are identified, many clinical tools are available to analyze benefit versus risk and guide pharmacy teams on how to safely discontinue specific medications and medication classes

The WHO defined a biomarker as any substance, structure, or process that can be measured in the body or its products and influence or predict the incidence of outcome or disease (WHO 2001)