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Semaglutide is an FDA-approved GLP-1 medication that lowers appetite and helps people with obesity or excess weight lose meaningful amounts of weight when paired with a reduced-calorie diet and regular activity
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Benefits of weight loss include: Reduction in knee joint loading Decrease in inflammatory mediators Improved mobility and physical function Reduction in pain severity Clinical evidence suggests that even 510% body weight reduction can significantly improve symptoms in patients with knee osteoarthritis
Chen, M
Another semaglutide injection, Wegovy, is FDA-approved for this purpose
Wegovy is an injectable form of semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist
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