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Niacinamide (Vitamin B3): A multi-functional active that refines body skin texture, minimizes the look of enlarged pores, and fortifies the moisture barrier for a resilient finish

It is not licensed by the MHRA and remains in Phase 3 clinical trials, with one programme expected to conclude in May 2026 [5][6]

It is not a hype signal

This is typically the fastest weight loss phase, with weekly losses of 1.2 to 1.8 pounds common at full doses

GLP-1 drugs like Ozempic and Wegovy, initially designed to treat diabetes and obesity, have grown into a phenomenon for weight loss

While GLP-1 therapies may reduce long-term risks of cardiovascular disease, diabetes complications, and disability, those benefits often accrue over decadeswell beyond the timeframe relevant to most employer plan sponsors