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In this aspect, treatments using long-acting dopaminergic agents or a continuous dopaminergic effect in the striatum have been associated with less severe motor complications, given alone or in combination with L-dopa [9]

This resistance allows LR3 to remain unbound and active in circulation for longer durations

doi: 10.7759/cureus.1004 217 ZhengXWangBTangXMaoBZhangQZhangTet al

and 150 mg kg 1 5FU (i.p.) alone or in combination with metformin

& Zarrouk, M