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The inhibitory effect of GLP-1 on glucagon secretion in vivo was observed only when the blood glucose level was equal to or higher than the fasting level, at higher blood glucose levels, the inhibition of glucagon gradually increased (Holst, 2007), and when the blood glucose concentration was less than 3.7 m mol/L, GLP-1 lost its effect on inhibiting glucagon secretion (Nauck et al., 2002)

Novo Nordisk, maker of the Wegovy pill, says the side effects of the oral option are similar to the injectable version

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It is commonly used in research settings as a diluent or solvent for reconstituting peptides, proteins, and other compounds

2009 Dec;161(6):895-902