Uno de los mecanismos mas extensamente estudiados implica su efecto sobre la angiogenesis, la formacin de nuevos vasos sanguineos, componente critico de la reparacin tisular
The peptide was also linked to higher levels of VEGF, a signal involved in blood vessel support, and to changes in cell signaling associated with keeping cells alive longer
Int J Pharm Pharm Sci 3 39.Singh M, Chitranshi N, Singh AP et al (2012) An overview on fast disintegrating sublingual tablets
NEJM 2011;365:15971604: 10.1056/NEJMoa1105816
Under conditions of metabolic stress, it migrates to the cell nucleus, where it activates a suite of genes governed by AMPK (AMP-activated protein kinase), the master cellular energy sensor
A 2001 Biochimica et Biophysica Acta paper anchored the foundational chelation chemistry of the tripeptide-copper system (PMID 11325542)