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In SURPASS-2, tirzepatide caused diarrhea in 13-16% of participants, while semaglutide 1 mg caused it in 12%

The Food and Drug Administration (FDA) has not approved Ozempic for weight management, but it has been shown to help manage body weight

If further results are needed, the healthcare provider might adjust the dose up to a maximum of 14 mg per day

Because semaglutide directly affects gut movement and the release of digestive enzymes, it can easily disrupt the natural rhythm of digestionespecially during the first few weeks of treatment

GLP-1 receptor agonists mimic some of its activity

Its key roles include triggering the release of insulin, blocking blood sugar spikes, slowing stomach emptying, and increasing fullness after eating