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The in-vivo biodistribution analysis corroborated these findings, revealing higher drug concentrations in the brain following intranasal administration of TER-NLC-ISGs than following intravenous administration of TER-NLCs

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However, these preclinical findings do not establish safety for use during human pregnancy, as species differences in placental transfer and fetal metabolism may exist

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Research suggests that BPC-157 may interact with cellular signaling pathways related to inflammation control, angiogenesis, and tissue integrity