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High-dose intraperitoneal N-acetylcysteine (800 mg/kg) induced acute liver, kidney, and spleen damage in mice, leading to mortality
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The IV Therapy treatment sessions last 45 minutes, while the NAD+ treatment sessions last between one hour to one hour and a half
Bzip, Basic Leucine Zipper Domain
As a side note, the observed modest response for the DMSO control was also incorporated into the model to take into account that a minor part of the pathway activation observed under the experimental conditions used is due to DMSO rather than DEM (see Supplement)
We have a constant demand for detoxification, so there needs to be a constant supply of glutathione
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