Briley-Saebo KC, et al
To ensure that findings are generalizable, key next steps will be to replicate and extend this work with variations of the target (e.g., gender, race/ethnicity, prior attempts at weight loss, cost paid for medication) and diverse groups of participants, both in terms of participant demographics and preexisting knowledge of GLP-1s (e.g., general population, eligible patients, healthcare professionals)
The complex interaction between all the factors does not allow definitive determination if OS is a primary cause or if it is a secondary effect to the propagation of damage in the nervous cells
PCOS often requires higher GLP-1 doses or adjunct metformin to achieve similar weight loss (Li 2023)
Independent self-learning or social media were the most frequently cited motivators, followed by advice from relatives or friends, pharmacists, and nutritionists
Prioritize protein intake, as it can help increase GLP-1 and shift eating patterns