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In this strain, the cytosolic sensor was more oxidized compared to the wt, however not to the extent found in a glr1 strain, while the matrix sensor exhibited a steady state almost identical to the sensor expressed in the wt background

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Statistical analysis The number of case groups with MTHFR genotypes ( CC, CT, and TT genotypes) and the number of controls were extracted from our pooled studies

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Illness, certain medications, and exposure to environmental pollutants can contribute to increased free radical production