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In UK primary care, patients with a B12 above 1,000 pmol/L had a one-year cancer incidence rate ratio of 4.72 compared with those in the reference range

In trials, it has produced weight loss exceeding 24% of baseline weight

Thus, these results showed a strong glucose-lowering effects towards a nearly-normal range with weight loss of a not previously reported extent in people with T2DM and without increased risk of clinically significant hypoglycemia [24]

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